The SIGNAL platform is designed to facilitate robust hit selection from normalized high-throughput datasets.

For a detailed user guide and sample dataset click on the “User Guide” tab.

Our manuscript describing the design, development, and testing of SIGNAL can be found here.

To cite: Katz, S., Song, J., Webb, K. P., Lounsbury, N. W., Bryant, C. E., & Fraser, I. D. C. (2021). SIGNAL: A web-based iterative analysis platform integrating pathway and network approaches optimizes hit selection from genome-scale assays. Cell Systems, 12(4), 338-352.e335. doi:

"Select up to 3 pathways for network graph analysis