SIGNAL - Selection by Iterative pathway Group and Network Analysis Looping

The SIGNAL platform is designed to facilitate robust hit selection from normalized high-throughput datasets.

For a detailed user guide and sample dataset click on the “User Guide” tab.

Our manuscript describing the design, development, and testing of SIGNAL can be found here.

To cite: Katz, S., Song, J., Webb, K. P., Lounsbury, N. W., Bryant, C. E., & Fraser, I. D. C. (2021). SIGNAL: A web-based iterative analysis platform integrating pathway and network approaches optimizes hit selection from genome-scale assays. Cell Systems, 12(4), 338-352.e335. doi:https://doi.org/10.1016/j.cels.2021.03.001

Mapped Genes
Unmapped Genes

Optional: Enter gene IDs that should be kept as high confidence hits throughout the analysis:

Gene ID type:

Entrez ID

Gene Symbol

"Select up to 3 pathways for network graph analysis

Your selected pathway IDs

Download all files

SIGNAL - Selection by Iterative pathway Group and Network Analysis Looping

The SIGNAL platform is designed to facilitate robust hit selection from normalized high-throughput datasets.

For a detailed user guide and sample dataset click on the “User Guide” tab.

Gene ID type:

"Select up to 3 pathways for network graph analysis

Version 2.0, last update: 12/14/2022, Privacy Policy, Disclaimer, Vulnerability Disclosure Policy